Detection of Breast Cancer Biomarker Increases Chances of Survival
Synthetic receptor-based Biosensing Platform for Protein Biomarkers
In the course of his master thesis Bernhard Auberger is working at the Molecular Electrochemistry Laboratory, led by Prof. Dr. Frederico Polo, at the Department of Molecular Sciences and Nanosystems - Ca' Foscari University in the beautiful lagoon city of Venice.
The focus is on the omnipresent topic of breast cancer, which is the most common cancer in women. In Austria, about 5,500 new cases are diagnosed annually and with a mortality rate of about 1,600, it is the highest cause of cancer death among women.
The aim of the project is to develop an electrochemical biosensing platform for the detection of the cancer biomarker h-uPA (breast cancer) in order to offer a faster POCT method in hospitals in the future. For this purpose, the applicability of a biosensor with peptides for the detection of protease upon binding of the biomarker h-uPA will be developed, investigated and identified.